AJNR: Applications of a Novel Microangioscope for Neuroendovascular Intervention

Preclinical evaluation in live animal and human cadaveric models assessing imaging quality, trackability, and navigability, with independent evaluator ratings suggesting usefulness in both diagnostic and interventional neuroendovascular applications.

Publication: AJNR American Journal of Neuroradiology 42(2):347-353 (2021). Epub Dec 24, 2020.

What it covers:
- Evaluated iterative microangioscope prototypes for neurodiagnostics and neurointerventions in live animal and human cadaveric models.
- Diagnostic assessments included clot identification/differentiation, plaque identification, vessel wall injury inspection, and stent apposition assessment.
- Interventions included angioscope-assisted stent-retriever thrombectomy, clot aspiration, and coil embolization.

Reported evaluator scoring (5-point scales):
- Imaging quality mean scores ranged approximately from 3.0 (clot identification) up to 4.7 (Pipeline follow-up).
- Clinical utility mean scores ranged approximately from 3.0 (aspiration thrombectomy) up to 4.7 (coil embolization and WEB device aneurysm treatment).

Peer-reviewed, Preclinical, Cadaveric model, In vivo animal model

Neuroendovascular intervention, Thrombectomy, Aspiration, Coil embolization, Stent apposition, Flow diverter follow-up, Aneurysm treatment

https://pubmed.ncbi.nlm.nih.gov/33361372/